Description

5-Amino-1MQ 5mg

Premium NNMT Inhibitor

Optimise your metabolic and cellular longevity research with our premium 5-Amino-1MQ 5mg. 5-Amino-1MQ (5-Amino-1-methylquinoline) is a small, selective, membrane-permeable molecule that functions as a potent inhibitor of nicotinamide N-methyltransferase (NNMT). NNMT is a cytosolic enzyme predominantly expressed in adipose tissue and the liver, where it acts as a master regulator of energy expenditure and metabolic homeostasis.

In laboratory models, the inhibition of NNMT by 5-Amino-1MQ reverses diet-induced obesity, accelerates intracellular macromolecule metabolism, and elevates NAD+ and ATP levels within cells. This 5mg high-purity vial is manufactured to strict laboratory standards, providing researchers with a highly stable and resilient compound for consistent in-vitro and in-vivo biochemical evaluation.

Product Features & Highlights

• Targeted NNMT Inhibition: Specifically blocks the NNMT enzyme to stimulate cellular energy expenditure without impacting other methyltransferase pathways.

• Adipocyte Metabolism Support: Heavily researched for its unique ability to shrink fat cells and alter fat tissue gene expression to enhance lipid oxidation.

• NAD+ and ATP Upregulation: Helps preserve intracellular NAD+ levels and drive cellular respiration, making it a primary compound for cellular longevity models.

• 99%+ Ultra-Purity: Every batch undergoes rigorous HPLC analysis to ensure complete structural integrity, maximum baseline stability, and zero filler compounds.

Dosage & Usage Instructions

Important Protocol Note: While 5-Amino-1MQ is commercially available in oral capsule forms for certain studies, this 5mg lyophilised format is specifically tailored for precise parenteral or in-vitro laboratory evaluation.

1. Standard Research Protocol

• Daily Dose: 500 mcg to 1 mg per day (adjusted proportionally based on the total mass of the subject model).

• Frequency: Administered as a single daily application, ideally at a consistent time each morning.

• Cycle Duration: Typically evaluated in research blocks of 4 to 8 weeks, followed by a 4-week clearance period to measure baseline metabolic changes and enzyme activity.

2. Reconstitution Directions

• Solvent: Gently introduce 2 ml of Sterile Water, Bacteriostatic Water, or a compatible laboratory buffer into the vial.

• Mixing: Do not shake the vial violently. Although 5-Amino-1MQ is a robust small molecule rather than a fragile long-chain peptide, it should still be handled carefully to prevent structural foaming. Slowly roll or swirl the vial between your palms until the lyophilised white powder completely dissolves into a clear, perfectly colourless liquid.

Storage, Handling & Shipping

• Lyophilised Powder (Unopened): Highly stable during standard transit temperatures. For long-term preservation, store in a refrigerator at 2°C to 8°C for up to 12 months, or freeze at -20°C for up to 2 years.

• Reconstituted Solution (Post-Mixing): Must be stored immediately in a refrigerator at 2°C to 8°C and shielded from direct ambient light. For peak biochemical stability, utilise the reconstituted vial within 30 days.

Product Specifications

Attribute	Specification
Purity (HPLC)	Minimum 99.0%
Concentration	5mg
Appearance	White to Off-White Lyophilised Powder
Molecular Formula	C10H11N2+
Chemical Name	5-amino-1-methylquinolin-1-ium
Form	1 Single-Dose/Multi-Dose Vial

Disclaimer: This product is sold exclusively for research, laboratory, and in-vitro development purposes. It is not intended or approved for direct human consumption.